Researchers Find Genetic Key to Safer, Long-Lasting Potatoes

**Scientists at UC Riverside have discovered a way to reduce steroidal glycoalkaloids (SGAs), toxic compounds found in potatoes, by targeting the protein GAME15.** Potatoes naturally produce SGAs as a defense against pests, but these compounds also make potatoes potentially harmful to humans when exposed to sunlight. The research team, led by Adam Jozwiak, explored the possibility of modifying plants to produce SGAs only in their leaves, leaving the edible parts safe for consumption. This advancement could reduce food waste and enhance the storage and transportation of potatoes. Additionally, the findings could revolutionize space farming, allowing all parts of the plant to be edible. The research involved a collaborative effort with international institutions, highlighting its global impact. By silencing the GAME15 gene in tomatoes, researchers observed a complete halt in SGA production but increased vulnerability to pests, indicating the critical role of this protein. Understanding this genetic mechanism allows for the potential redesign of crops, ensuring both safety and resilience. This breakthrough not only promises healthier food options but also represents a significant step forward in sustainable agriculture and space exploration.